Motif ID: HOX{A4,D4}.p2

Z-value: 1.367


Transcription factors associated with HOX{A4,D4}.p2:

Gene SymbolEntrez IDGene Name
Hoxa4 15401 homeobox A4
Hoxd4 15436 homeobox D4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hoxd4chr2_+_74560034-0.206.3e-03Click!
Hoxa4chr6_-_521416970.018.5e-01Click!


Activity profile for motif HOX{A4,D4}.p2.

activity profile for motif HOX{A4,D4}.p2


Sorted Z-values histogram for motif HOX{A4,D4}.p2

Sorted Z-values for motif HOX{A4,D4}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOX{A4,D4}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_69487700 31.171 Ank3
ankyrin 3, epithelial
chr5_-_122906470 28.190 Atp2a2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chrX_+_133357268 24.343 NM_011123
 Plp1
proteolipid protein (myelin) 1
chr17_+_71168939 23.795 Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr11_+_56825307 21.677 Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr16_+_7069971 21.595 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr11_+_56825258 21.243 Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr5_-_122907002 20.888 Atp2a2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr7_-_107810868 20.027 NM_001163182
NM_013746
 Plekhb1

pleckstrin homology domain containing, family B (evectins) member 1

chr12_+_110784600 19.877 Meg3
maternally expressed 3
chr11_+_56825192 19.766 NM_001113325
NM_008165
 Gria1

glutamate receptor, ionotropic, AMPA1 (alpha 1)

chr16_+_7069927 19.580 NM_183188
 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr12_+_91570569 19.105 Nrxn3
neurexin III
chr12_+_30219769 18.605 NM_001093776
 Myt1l
myelin transcription factor 1-like
chr2_+_177910053 18.451 NM_001177791
 Phactr3
phosphatase and actin regulator 3
chr4_+_101180625 17.882 Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr10_+_69488049 17.857 Ank3
ankyrin 3, epithelial
chr9_-_91255831 17.552 Zic1
zinc finger protein of the cerebellum 1
chr5_+_89012596 17.420 NM_027530
 Rufy3
RUN and FYVE domain containing 3
chr13_+_42775991 17.223 NM_198419
 Phactr1
phosphatase and actin regulator 1

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Showing 1 to 18 of 18 entries
Enrichment   P-value GO Accession GO Term
2.78 4.16e-02 GO:0043292 contractile fiber
2.49 2.18e-04 GO:0030425 dendrite
2.41 1.73e-03 GO:0030424 axon
2.40 9.54e-05 GO:0044297 cell body
2.39 2.02e-04 GO:0043025 neuronal cell body
2.38 5.49e-07 GO:0045202 synapse
2.37 1.75e-04 GO:0044456 synapse part
2.12 1.95e-05 GO:0043005 neuron projection
1.95 6.25e-07 GO:0005626 insoluble fraction
1.93 3.56e-06 GO:0005624 membrane fraction
1.87 1.17e-07 GO:0000267 cell fraction
1.68 2.62e-03 GO:0044430 cytoskeletal part
1.61 1.04e-04 GO:0005856 cytoskeleton
1.56 1.50e-02 GO:0042995 cell projection
1.52 2.07e-02 GO:0031090 organelle membrane
1.41 1.27e-06 GO:0071944 cell periphery
1.39 4.92e-06 GO:0005886 plasma membrane
1.16 1.14e-02 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
Enrichment   P-value GO Accession GO Term
2.12 1.12e-04 GO:0008092 cytoskeletal protein binding
2.09 4.45e-02 GO:0003779 actin binding
1.29 1.34e-05 GO:0005515 protein binding
1.14 7.35e-04 GO:0005488 binding